The Graduated Program in Bacteriology is situated at the heart of a dense collection of biomedical research facilities. GPiB students have access to the latest technologies and support services, no matter their research interests. Exhaustive lists of available resources are available through HMS and the Harvard Catalyst, and a few are highlighted below.
MICRON Floating Microscopy Core
Centered in the Department of Microbiology at HMS, the MICRON Core maintains a network of wide-field and confocal microscopes. A dedicated PhD-trained scientist and her staff train users and provide practical advice on how to best incorporate microscopy-based experiments to address research questions. All GPiB students have access to this core.
The Harvard Medical School EM Facility is a fee-for-service core facility open to researchers in the HMS Quadrangle and the Longwood Medical area. The Facility provides services and supervision in Transmission Electron Microscopy.
Nikon Imaging Center
The Nikon Imaging Center (NIC) is a core light microscopy facility developed in partnership with Nikon Instruments Inc. and Micro Video Instruments Inc. The NIC@HMS maintains a wide range of light microscopy stations, including laser scanning confocal, spinning disk confocal, TIRF, STORM, and Structured illumination Microscopy. The core provides theoretical and practical training.
Harvard Chan Bioinformatics Core
The HSPH Bioinformatics Core (HCBC) offers consultations in research computing, bioinformatic,s and computational biology during the initial stages of study design and throughout research projects.
ICCB-Longwood Screening Facility
The ICCB-Longwood Investigator Initiated Screening Program assists academic researchers in carrying out high-throughput screens of chemical and RNAi libraries to identify new tools for biological research. The ICCB-Longwood maintains a library of >250,000 compounds, including >8,000 'known bioactive' compounds, many of which have been characterized in animal models or in the clinic. Human and mouse whole-genome siRNA, and miRNA mimic and inhibitor libraries are also available for RNAi screening.
Center for Macromolecular Interactions
The Center for Macromolecular Interactions (CMI) in the HMS Department of Biological Chemistry and Molecular Pharmacology provides scientific consultation, training, and access to shared biophysical equipment for the characterization and analysis of macromolecules and their complexes. The facility currently includes instruments for Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Circular Dichroism (CD), Analytical Size Exclusion Chromatography for Multi-Angle Light Scattering (SEC-MALS) or Fluorescence detection (FSEC).